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Product Details
14737-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DNM3 Fusion Protein Ag6381 (206-555 aa encoded by BC064546)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Western blot using this antibody specifically detected the 100 kDa DNM3 in mouse brain. It doesn't cross-react with other DNMs.
Immunogen sequence: KLDLMDEGT DARDVLENKL LPLRRGYVGV VNRSQKDIDG KKDIKAAMLA ERKFFLSHPA YRHIADRMGT PHLQKVLNQQ LTNHIRDTLP NFRNKLQGQL LSIEHEVEAY KNFKPEDPTR KTKALLQMVQ QFAVDFEKRI EGSGDQVDTL ELSGGAKINR IFHERFPFEI VKMEFNEKEL RREISYAIKN IHGIRTGLFT PDMAFEAIVK KQIVKLKGPS LKSVDLVIQE LINTVKKCTK KLANFPRLCE ETERIVANHI REREGKTKDQ VLLLIDIQVS YINTNHEDFI GFANAQQRSS QVHKKTTVGN QVIRKGWLTI SNIGIMKGGS KGYWFVLTAE SLSWYKDDEN I (206-555 aa encoded by BC064546)
Target Information
The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dyna III; dynamin family member; Dynamin III; Dynamin, testicular; Dynamin-3; T-dynamin; testicular dynamin
Gene Aliases: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; DNM3; Dyn3; Dyna III; dynamin-2; KIAA0820; mKIAA0820
UniProt ID: (Human) Q9UQ16, (Mouse) Q8BZ98, (Rat) Q08877
Entrez Gene ID: (Human) 26052, (Mouse) 103967, (Rat) 171574
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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