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Product Details
PA5-68163
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human DOCK7.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2691875
Product Specific Information
Predicted to react with Mouse samples.
Target Information
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dedicator of cytokinesis protein 7; protein moonlight
Gene Aliases: 3110056M06Rik; DOCK7; EIEE23; Gm430; KIAA1771; m; ZIR2
UniProt ID: (Human) Q96N67
Entrez Gene ID: (Human) 85440, (Mouse) 67299
microtubule cytoskeleton organization
small GTPase mediated signal transduction
axonogenesis
interkinetic nuclear migration
neuron projection development
positive regulation of peptidyl-serine phosphorylation
establishment of neuroblast polarity
regulation of neurogenesis
activation of GTPase activity
positive regulation of vascular associated smooth muscle cell migration
hematopoietic progenitor cell differentiation
multicellular organism development
nervous system development
cell differentiation
pigmentation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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