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Product Details
PA5-38049
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
17 amino acid peptide near the carboxy terminus of human DOCK8
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2554653
Product Specific Information
A recommended positive control is EL4 cell lysate.
Multiple isoforms of DOCK8 are known to exist.
Target Information
The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors. DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1200017A24Rik; Dedicator of cytokinesis protein 8; epididymis luminal protein 205
Gene Aliases: 1200017A24Rik; 5830472H07Rik; A130095G14Rik; AI461977; DOCK8; HEL-205; MRD2; ZIR8
UniProt ID: (Human) Q8TEP1, (Mouse) Q8C147
Entrez Gene ID: (Human) 81704, (Mouse) 76088, (Rat) 499337
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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