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Product Details
14087-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DOK2 Fusion Protein Ag5218 (1-412 aa encoded by BC032623)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGDGAVKQG FLYLQQQQTF GKKWRRFGAS LYGGSDCALA RLELQEGPEK PRRCEAARKV IRLSDCLRVA EAGGEASSPR DTSAFFLETK ERLYLLAAPA AERGDWVQAI CLLAFPGQRK ELSGPEGKQS RPCMEENELY SSAVTVGPHK EFAVTMRPTE ASERCHLRGS YTLRAGESAL ELWGGPEPGT QLYDWPYRFL RRFGRDKVTF SFEAGRRCVS GEGNFEFETR QGNEIFLALE EAISAQKNAA PATPQPQPAT IPASLPRPDS PYSRPHDSLP PPSPTTPVPA PRPRGQEGEY AVPFDAVARS LGKNFRGILA VPPQLLADPL YDSIEETLPP RPDHIYDEPE GVAALSLYDS PQEPRGEAWR RQATADRDPA GLQHVQPAGQ DFSASGWQPG TEYDNVVLKK GPK (1-412 aa encoded by BC032623)
Target Information
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok-R; Dok-related protein; Downstream of tyrosine kinase 2; FRIP; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; p56 dok-2; p56(dok-2)
Gene Aliases: Dok-2; DOK2; DokR; Frip; p56DOK; p56dok-2
UniProt ID: (Human) O60496, (Mouse) O70469
Entrez Gene ID: (Human) 9046, (Rat) 290361, (Mouse) 13449
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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