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Product Details
PA5-62201
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DPP6. Recombinant protein control fragment (Product #RP-101264).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2640774
Product Specific Information
Immunogen sequence: VKKAINDRQM PKVEYRDIEI DDYNLPMQIL KPATFTDTTH YPLLLVVDGT PGSQSVAEKF EVSWETVMVS SHGAVVVKCD G
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Target Information
DPP6 encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-type potassium channel modulatory protein DPP6; dipeptidyl aminopeptidase IV-related protein; Dipeptidyl aminopeptidase-like protein 6; Dipeptidyl aminopeptidase-related protein; Dipeptidyl peptidase 6; Dipeptidyl peptidase IV-like protein; dipeptidyl peptidase IV-related protein; Dipeptidyl peptidase VI; dipeptidyl-peptidase 6; dipeptidylpeptidase VI; DPP VI; DPPX; In(5)6H p; inversion, Chr 5, Harwell 6, proximal
Gene Aliases: B930011P16Rik; D5Buc3; D5Buc4; D5Buc5; DPL1; DPP VI; Dpp-6; DPP6; DPPX; Gm1377; In(5)6H-p; MRD33; Peplb; Rw; VF2
UniProt ID: (Human) P42658, (Mouse) Q9Z218
Entrez Gene ID: (Human) 1804, (Mouse) 13483
proteolysis
positive regulation of potassium ion transport
protein localization to plasma membrane
regulation of potassium ion transmembrane transport
neuronal action potential
regulation of membrane potential
regulation of potassium ion transport
positive regulation of establishment of protein localization to plasma membrane
positive regulation of potassium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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