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Product Details
PA5-76327
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human DRD5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2720054
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: D(1B) dopamine receptor; D(5) dopamine receptor; D1b receptor; D1beta dopamine receptor; Dopamine 5 receptor; Dopamine D5 receptor; dopamine receptor D1B; DRD 1B; DRD 5; Hd5dr; MGC10601
Gene Aliases: D5R; DBDR; Drd-5; DRD1B; DRD1L2; DRD5; Gpcr1
UniProt ID: (Human) P21918, (Mouse) Q8BLD9
Entrez Gene ID: (Human) 1816, (Mouse) 13492
synaptic transmission, dopaminergic
response to amphetamine
regulation of systemic arterial blood pressure by vasopressin
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
cellular calcium ion homeostasis
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-activating dopamine receptor signaling pathway
chemical synaptic transmission
learning
associative learning
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
transmission of nerve impulse
negative regulation of NAD(P)H oxidase activity
wound healing
response to cocaine
positive regulation of adenylate cyclase activity
negative regulation of blood pressure
regulation of female receptivity
sensitization
phospholipase C-activating dopamine receptor signaling pathway
long term synaptic depression
cellular response to catecholamine stimulus
reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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