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FIGURE: 1 / 1
DSPP Antibody (PA5-109663) in WB
Western blot analysis of DSPP in extracts of various cell lines. Samples were incubated with DSPP Polyclonal antibody (Product # PA5-109663) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-109663
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 16-146 of human DSPP (NP_055023.2).
Conjugate
Form
Liquid
Concentration
2.09 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855074
Product Specific Information
Immunogen sequence: IPVPQSKPLE RHVEKSMNLH LLARSNVSVQ DELNASGTIK ESGVLVHEGD RGRQENTQDG HKGEGNGSKW AEVGGKSFST YSTLANEEGN IEGWNGDTGK AETYGHDGIH GKEENITANG IQGQVSIIDN A
Target Information
This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dentin matrix protein 3; dentin phosphophoryn; dentin phosphoprotein; dentin phosphoryn; dentin sailophosphoprotein; Dentin sialophosphoprotein; Dentin sialoprotein; Dentine sialoprotein; DMP-3; DTDP2
Gene Aliases: DFNA39; DGI1; Dmp2; DMP3; DPP; DSP; DSPP; RDSP2
UniProt ID: (Human) Q9NZW4
Entrez Gene ID: (Human) 1834, (Rat) 25254, (Mouse) 666279
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