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Product Details
PA5-50494
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human deltex homolog 1 (Drosophila)
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2635947
Product Specific Information
The antibody detects endogenous levels of total DTX1 protein.
Target Information
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deltex 1; deltex 1, E3 ubiquitin ligase; deltex homolog 1; Deltex1; E3 ubiquitin-protein ligase DTX1; fractionated x-irradiation induced transcript 1; FXI-T1; hDTX1; mDTX1; Protein deltex-1; RING-type E3 ubiquitin transferase DTX1
Gene Aliases: DTX1; Fxit1; hDx-1; mKIAA4160
UniProt ID: (Human) Q86Y01, (Mouse) Q61010
Entrez Gene ID: (Human) 1840, (Mouse) 14357
transcription coactivator activity
Notch binding
protein binding
zinc ion binding
ligase activity
SH3 domain binding
ubiquitin protein ligase binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
transcription, DNA-templated
transcription from RNA polymerase II promoter
cell surface receptor signaling pathway
Notch signaling pathway
regulation of Notch signaling pathway
glial cell differentiation
protein ubiquitination
negative regulation of T cell differentiation
negative regulation of neuron differentiation
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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