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Product Details
25222-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DTX4 Fusion Protein Ag18415 (51-213 aa encoded by BC119011)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LDLIYPMVT GTLPKAQSWP VSPGPATSPP MSPCSCPQCV LVMSVKAAVV NGSTGPLQLP VTRKNMPPPG VVKLPPLPGS GAKPLDSTGT IRGPLKTAPS QVIRRQASSM PTGTTMGSPA SPPGPNSKTG RVALATLNRT NLQRLAIAQS RVLIASGVPT VPVK (51-213 aa encoded by BC119011)
Target Information
DTX4 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deltex 4 homolog; deltex 4, E3 ubiquitin ligase; deltex homolog 4; Deltex4; E3 ubiquitin-protein ligase DTX4; Protein deltex-4; RING finger protein 155; RING-type E3 ubiquitin transferase DTX4
Gene Aliases: AI449438; BC044798; D930042H13; DTX4; KIAA0937; RNF155
UniProt ID: (Human) Q9Y2E6, (Mouse) Q6PDK8
Entrez Gene ID: (Human) 23220, (Mouse) 207521
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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