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Product Details
26910-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DUSP7/PYST2 Fusion Protein Ag25488 (60-102 aa encoded by BC104880)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IRSIIPNHA DKERFATRCK AATVLLYDEA TAEWQPEPGA PASV (60-102 aa encoded by BC104880)
Target Information
DUSP7 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dual specificity protein phosphatase 7; Dual specificity protein phosphatase MKP-X; Dual specificity protein phosphatase PYST2; dual-specificity phosphatase-7; MAP kinase phosphatase
Gene Aliases: AU015694; DUSP7; mkp-X; MKPX; PYST2
UniProt ID: (Human) Q16829, (Mouse) Q91Z46, (Rat) Q63340
Entrez Gene ID: (Human) 1849, (Mouse) 235584, (Rat) 300980
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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