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DYNC1I1 Antibody (PA5-116993) in IHC (P)
Immunohistochemistry analysis of DYNC1I1 in paraffin-embedded human stomach. Samples were incubated with DYNC1I1 Polyclonal antibody (Product # PA5-116993) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116993
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DYNC1I1 (NP_0011290281)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901623
Product Specific Information
Positive Samples: Jurkat, SH-SY5Y, HeLa, Mouse testis, Mouse brain, Mouse skeletal muscle, Rat brain, Rat testis
Immunogen sequence: MSDKSDLKAE LERKKQRLAQ IREEKKRKEE ERKKKEADMQ QKKEPVQDDS DLDRKRRETE ALLQSIGISP EPPLVPTPMS PSSKSVSTPS EAGSQDSGDL GPLTRTLQWD TDPSVLQLQS DSELGRRLHK LGVSKVTQVD FLPREVVSYS KETQTPLATH QSEEDEEDEE MVESKVGQDS ELENQDKKQE VKEAPPRELT EEEKQQILHS EEFLIFFDRT
Target Information
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; cytoplasmic dynein intermediate chain 1 isoform 1.6; DH IC-1; Dnci 1; Dynein intermediate chain 1, cytosolic; Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic dynein intermediate chain 1); dynein, cytoplasmic 1, intermediate chain 1; dynein, cytoplasmic, intermediate chain 1; dynein, cytoplasmic, intermediate polypeptide 1
Gene Aliases: DH IC-1; DHIC-1; DIC; DNCI1; DNCIC1; DYNC1I1; IC74
UniProt ID: (Human) O14576, (Mouse) O88485, (Rat) Q63100
Entrez Gene ID: (Human) 1780, (Mouse) 13426, (Rat) 29564
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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