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Product Details
12240-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DYRK1B Fusion Protein Ag2883 (38-343 aa encoded by BC018751)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RDATSAPLR KLSVDLIKTY KHINEVYYAK KKRRAQQAPP QDSSNKKEKK VLNHGYDDDN HDYIVRSGER WLERYEIDSL IGKGSFGQVV KAYDHQTQEL VAIKIIKNKK AFLNQAQIEL RLLELMNQHD TEMKYYIVHL KRHFMFRNHL CLVFELLSYN LYDLLRNTHF RGVSLNLTRK LAQQLCTALL FLATPELSII HCDLKPENIL LCNPKRSAIK IVDFGSSCQL GQRIYQYIQS RFYRSPEVLL GTPYDLAIDM WSLGCILVEM HTGEPLFSGS NEVDQMNRIV EVLGIPPAAM LDQAPKA (38-343 aa encoded by BC018751)
Target Information
DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for the laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRKB; Minibrain-related kinase; Mirk protein kinase
Gene Aliases: AOMS3; DYRK1B; MIRK
UniProt ID: (Human) Q9Y463, (Mouse) Q9Z188
Entrez Gene ID: (Human) 9149, (Mouse) 13549, (Rat) 308468
transcription coactivator activity
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
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