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Antibody detects endogenous levels of total DYX1C1.
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternate splicing results in multiple transcript variants.
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Protein Aliases: Dynein axonemal assembly factor 4; dynein, axonemal, assembly factor 4; dyslexia susceptibility 1 candidate 1 homolog; Dyslexia susceptibility 1 candidate gene 1 protein; Dyslexia susceptibility 1 candidate gene 1 protein homolog; FLJ37882; MGC70618
Gene Aliases: 1700010I24Rik; b2b811Clo; CILD25; DNAAF4; DYX1; DYX1C1; DYXC1; Edem2; EKN1; RD
UniProt ID: (Human) Q8WXU2, (Rat) Q5VJS5, (Mouse) Q8R368
Entrez Gene ID: (Human) 161582, (Rat) 363096, (Mouse) 67685
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