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Product Details
PA5-103783
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DSG4(Accession Q86SJ6), corresponding to amino acid residues S251-D301.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853116
Product Specific Information
Antibody detects endogenous levels of total DSG4.
Target Information
Desmoglein proteins are cadherin-type cell adhesion molecules. Desmoglein 4 (dsg4) shares 41% identity with human desmoglein 1, 37% with human desmoglein 2 and 50% with human desmoglein 3. A type I membrane protein of the cadherin protein family, dsg4 is expressed in salivary gland, suprabasal epidermis, hair follicle, testis, prostate and skin. In the hair follicle, dsg4 is an important mediator of keratinocyte cell adhesion and coordinates the transition from proliferation to differentiation. The human DSG4 gene is composed of 16 exons spanning approximately 37 kb of 18q12 and is situated between DSG1 and DSG3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cadherin family member 13; Desmoglein-4; Desmoglein4; lanceolate hair
Gene Aliases: CDGF13; CDHF13; DSG4; HYPT6; LAH
UniProt ID: (Human) Q86SJ6, (Mouse) Q7TMD7, (Rat) Q6W3B0
Entrez Gene ID: (Human) 147409, (Mouse) 16769, (Rat) 291754
Performance Guarantee
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