Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
D5R-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 428-478 on mouseDopamine Receptor D5 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: D(1B) dopamine receptor; D(5) dopamine receptor; D1b receptor; Dopamine 5 receptor; Dopamine D5 receptor; dopamine receptor 5; DRD 1B; DRD 5; Hd5dr; MGC10601
Gene Aliases: D1B; D5R; Drd-5; Drd1b; Drd5; Gpcr1
UniProt ID: (Mouse) Q8BLD9, (Rat) P25115
Entrez Gene ID: (Mouse) 13492, (Rat) 25195
synaptic transmission, dopaminergic
response to amphetamine
regulation of systemic arterial blood pressure by vasopressin
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
negative regulation of protein kinase activity
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
dopamine receptor signaling pathway
chemical synaptic transmission
mating behavior
associative learning
visual learning
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
transmission of nerve impulse
negative regulation of cell migration
positive regulation of cAMP biosynthetic process
negative regulation of NAD(P)H oxidase activity
wound healing
response to cocaine
positive regulation of adenylate cyclase activity
negative regulation of blood pressure
regulation of female receptivity
sensitization
regulation of long-term neuronal synaptic plasticity
long term synaptic depression
cellular response to catecholamine stimulus
reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support