Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
14222-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ECEL1 Fusion Protein Ag5460 (425-775 aa encoded by BC050453)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AQEMEGSDK PQELARVCLG QANRHFGMAL GALFVHEHFS AASKAKVQQL VEDIKYILGQ RLEELDWMDA ETRAAARAKL QYMMVMVGYP DFLLKPDAVD KEYEFEVHEK TYFKNILNSI RFSIQLSVKK IRQEVDKSTW LLPPQALNAY YLPNKNQMVF PAGILQPTLY DPDFPQSLNY GGIGTIIGHE LTHGYDDWGG QYDRSGNLLH WWTEASYSRF LRKAECIVRL YDNFTVYNQR VNGKHTLGEN IADMGGLKLA YHAYQKWVRE HGPEHPLPRL KYTHDQLFFI AFAQNWCIKR RSQSIYLQVL TDKHAPEHYR VLGSVSQFEE FGRAFHCPKD SPMNPAHKCS VW (425-775 aa encoded by BC050453)
Target Information
This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: damage induced neuronal endopeptidase; Damage-induced neuronal endopeptidase; endothelin converting enzyme-like 1; Endothelin-converting enzyme-like 1; metallopeptidase; X converting enzyme; Xce protein
Gene Aliases: DA5D; DINE; ECEL1; ECEX; UNQ2431/PRO4991; XCE
UniProt ID: (Human) O95672, (Mouse) Q9JMI0, (Rat) Q9JHL3
Entrez Gene ID: (Human) 9427, (Mouse) 13599, (Rat) 60417
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support