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Del-1 is an integrin ligand that is expressed by endothelial cells during embryological vascular development. It promotes adhesion of endothelial cells through an interaction with the alpha-v/beta-3 integrin receptor. Del-1 plays a vital role in mediating angiogenesis.
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Protein Aliases: developmental endothelial locus-1; Developmentally-regulated endothelial cell locus 1 protein; EGF-like repeat and discoidin I-like domain-containing protein 3; EGF-like repeats and discoidin I-like domains 3; Integrin-binding protein DEL1
Gene Aliases: Del-1; DEL1; EDIL3
UniProt ID: (Human) O43854, (Mouse) O35474
Entrez Gene ID: (Human) 10085, (Mouse) 13612, (Rat) 688400
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