Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-17794
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly,
Human,
Mouse,
Non-human primate,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues at the amino-terminus of human eEF2
Conjugate
Form
Liquid
Concentration
11.7 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10984649
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EF-2; Elongation factor 2; elongation factor-2; polypeptidyl-tRNA translocase
Gene Aliases: EEF-2; EEF2; EF-2; EF2; SCA26
UniProt ID: (Human) P13639, (Mouse) P58252, (Rat) P05197
Entrez Gene ID: (Human) 1938, (Mouse) 13629, (Rat) 29565
p53 binding
translation elongation factor activity
GTPase activity
protein binding
GTP binding
5S rRNA binding
protein kinase binding
ribosome binding
poly(A) RNA binding
actin filament binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
translation activator activity
translation elongation factor
hematopoietic progenitor cell differentiation
response to ischemia
skeletal muscle contraction
translational elongation
aging
glial cell proliferation
response to fluoxetine
peptidyl-diphthamide biosynthetic process from peptidyl-histidine
response to estradiol
response to endoplasmic reticulum stress
skeletal muscle cell differentiation
response to hydrogen peroxide
response to ethanol
positive regulation of translation
response to folic acid
cell-cell adhesion
cellular response to brain-derived neurotrophic factor stimulus
positive regulation of cytoplasmic translation
translation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support