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Product Details
BS-11743R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ELAVL2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Anti-Hu antibodies were originally isolated from a patient with paraneoplastic encephalomyelitis, a rare condition of selective neural tissue injury associated with small cell lung carcinoma. The antibodies bind specifically to antigens present exclusively in neuronal cells and are thus useful as markers of neuronal cells in tissue. The Hu antigen is an RNA-binding protein of the embryonic lethal abnormal visual (Elav) family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV-like neuronal protein 1; ELAV-like neuronal protein 1 isoform Hel-N2; ELAV-like protein 2; ELAV-like protein 4; ELAVL3; embryonic lethal, abnormal vision-like 2; Hu antigen D; HU-antigen B; HU-antigen D; HuB; HuD; Nervous system-specific RNA-binding protein Hel-N1; Nervous system-specific RNA-binding protein Mel-N1; Paraneoplastic encephalomyelitis antigen HuD; PLE21; RNA binding protein HuB; RNA-binding protein HUD3
Gene Aliases: Elav; Elav2; ELAVL2; ELAVL4; HEL-N1; HELN1; HUB; HUD; mel-N1; PNEM; r-HuD; RGD1561943
UniProt ID: (Human) Q12926, (Human) P26378, (Mouse) Q60899, (Mouse) Q61701, (Rat) O09032
Entrez Gene ID: (Human) 1993, (Human) 1996, (Mouse) 15569, (Rat) 286973, (Mouse) 15572, (Rat) 432358
mRNA splicing, via spliceosome
regulation of transcription, DNA-templated
RNA processing
mRNA processing
learning
locomotory behavior
neuron differentiation
regulation of mRNA stability
dendrite morphogenesis
positive regulation of dendrite development
nervous system development
aging
associative learning
regeneration
response to endoplasmic reticulum stress
response to cocaine
cellular response to nerve growth factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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