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Antibody detects endogenous levels of total StIp1.
ELP2 regulates the ligand-dependent activation of STAT3. The protein acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
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Protein Aliases: elongation protein 2 homolog; Elongator complex protein 2; elongator protein 2; ELP2; SHINC-2; signal transducer and activator of transcription 3 interacting protein 1; signal transducer and activator of transcription interacting protein 1; STAT3-interacting protein 1; StIP1
Gene Aliases: AU023723; ELP2; Epl2; SHINC-2; STATIP1; StIP; StIP1
UniProt ID: (Human) Q6IA86, (Mouse) Q91WG4, (Rat) Q496Z0
Entrez Gene ID: (Human) 55250, (Mouse) 58523, (Rat) 307545
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