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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
EME1 and MUS81 form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Crossover junction endonuclease EME1; essential meiotic endonuclease 1 homolog 1; essential meiotic endonuclease 1 homolog 2; hMMS4; homolog of yeast EME1 endonuclease; MMS4 homolog; Msm4; SLX2 structure-specific endonuclease subunit homolog A
Gene Aliases: 6820428D13; EME1; MMS4; MMS4L; SLX2A
UniProt ID: (Human) Q96AY2, (Mouse) Q8BJW7
Entrez Gene ID: (Human) 146956, (Mouse) 268465, (Rat) 287634
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