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Product Details
MA5-15757
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
7G1G10
Immunogen
Recombinant protein corresponding to amino acids 51 - 140 of human EndoG.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11154474
Product Specific Information
A suggested positive control is HepG2 cell lysate.
Target Information
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endo G; Endonuclease G, mitochondrial; mitochondrial endonuclease G
Gene Aliases: ENDOG
UniProt ID: (Human) Q14249
Entrez Gene ID: (Human) 2021, (Rat) 362100
in utero embryonic development
apoptotic DNA fragmentation
DNA recombination
aging
response to mechanical stimulus
response to estradiol
response to tumor necrosis factor
neuron death in response to oxidative stress
response to antibiotic
cellular response to calcium ion
cellular response to glucose stimulus
cellular response to hypoxia
positive regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of apoptotic DNA fragmentation
cellular response to oxidative stress
positive regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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