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Invitrogen
Ephrin A1 Recombinant Rabbit Monoclonal Antibody (5D4Q5)
Product Details
MA5-42911
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5D4Q5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ephrin A1 (P20827).
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2912052
Product Specific Information
Positive test controls include: HepG2.
Immunogen sequence: MEFLWAPLLG LCCSLAAADR HTVFWNSSNP KFRNEDYTIH VQLNDYVDII CPHYEDHSVA DAAMEQYILY LVEHEEYQLC QPQSKDQVRW QCNRPSAKHG
Target Information
This gene encodes a member of the ephrin family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EPH-related receptor tyrosine kinase ligand 1; Ephrin-A1; Immediate early response protein B61; LERK-1; ligand of eph-related kinase 1; TNF alpha-induced protein 4; Tumor necrosis factor alpha-induced protein 4; tumor necrosis factor, alpha-induced protein 4
Gene Aliases: AI325262; B61; ECKLG; EFL1; EFNA1; Epgl1; Epl1; EPLG1; LERK-1; LERK1; TNFAIP4
UniProt ID: (Human) P20827, (Mouse) P52793
Entrez Gene ID: (Human) 1942, (Mouse) 13636
negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
angiogenesis
aortic valve morphogenesis
mitral valve morphogenesis
endocardial cushion to mesenchymal transition involved in heart valve formation
cell-cell signaling
axon guidance
negative regulation of epithelial to mesenchymal transition
notochord formation
cell migration
regulation of cell adhesion mediated by integrin
substrate adhesion-dependent cell spreading
regulation of blood vessel endothelial cell migration
regulation of angiogenesis
ephrin receptor signaling pathway
regulation of peptidyl-tyrosine phosphorylation
positive regulation of peptidyl-tyrosine phosphorylation
regulation of axonogenesis
negative regulation of dendritic spine morphogenesis
neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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