Proteintech

FABP1 Polyclonal Antibody

FIGURE: 1 / 4

FABP1 Antibody (13626-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with (Product # 13626-1-AP) (FABP1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

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Product Details

13626-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 16 publications 16 publications

Immunohistochemistry (IHC)

Assay-dependent

View 2 publications 2 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FABP1 Fusion Protein Ag4540 (1-127 aa encoded by BC032801)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSFSGKYQL QSQENFEAFM KAIGLPEELI QKGKDIKGVS EIVQNGKHFK FTITAGSKVI QNEFTVGEEC ELETMTGEKV KTVVQLEGDN KLVTTFKNIK SVTELNGDII TNTMTLGDIV FKRISKRI (1-127 aa encoded by BC032801)

Target Information

FABP1 encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.

Journal of medicinal chemistry

Deng Y,Dong G,Meng Y,Noinaj N,Huang R

Thu Jan 26 00:00:00 EST 2023

Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.

Life sciences

Zhou X,Li Y,Yang C,Chen D,Wang T,Liu T,Yan W,Su Z,Peng B,Ren X

Tue Aug 15 00:00:00 EDT 2023

Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells.

Journal of dairy science

Chen H,Qi X,Guan K,Wang R,Li Q,Ma Y

Sat Apr 01 00:00:00 EDT 2023

Millet Bran Protein Hydrolysate Displays the Anti-non-alcoholic Fatty Liver Disease Effect via Activating Peroxisome Proliferator-Activated Receptor γ to Restrain Fatty Acid Uptake.

Journal of agricultural and food chemistry

Shan S,Zhou J,Yin R,Zhang L,Shi J,Qiao Q,Li Z

Wed Jan 25 00:00:00 EST 2023

Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.

iScience

Li H,Du Y,Ji H,Yang Y,Xu C,Li Q,Ran L,Wu C,Zhou Q,Wu S

Fri Nov 18 00:00:00 EST 2022

Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.

iScience

Li H,Du Y,Ji H,Yang Y,Xu C,Li Q,Ran L,Wu C,Zhou Q,Wu S

Fri Nov 18 00:00:00 EST 2022

PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.

Biochemical pharmacology

Xu Y,Denning KL,Lu Y

Fri Oct 01 00:00:00 EDT 2021

Proteome analysis identified proteins associated with mitochondrial function and inflammation activation crucially regulating the pathogenesis of fatty liver disease.

BMC genomics

Zhang L,Liu T,Hu C,Zhang X,Zhang Q,Shi K

Sat Sep 04 00:00:00 EDT 2021

Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.

Frontiers in oncology

Lu J,Zhang Y,Sun M,Ding C,Zhang L,Kong Y,Cai M,Miccoli P,Ma C,Yue X

Fri Apr 29 00:00:00 EDT 2022

PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.

Free radical biology & medicine

Chen X,Xu Y,Denning KL,Grigore A,Lu Y

Tue Jun 01 00:00:00 EDT 2021

N¹-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism.

Nature communications

Wang Y,Wang J,Li X,Xiong X,Wang J,Zhou Z,Zhu X,Gu Y,Dominissini D,He L,Tian Y,Yi C,Fan Z

Tue Nov 02 00:00:00 EDT 2021

MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.

Biomaterials

Song M,Zhang S,Tao Z,Li J,Shi Y,Xiong Y,Zhang W,Liu C,Chen S

Mon Nov 01 00:00:00 EDT 2021

Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in mice.

International journal of oncology

Ye L,Chen T,Cao J,Sun L,Li W,Zhang C

Sun Nov 01 00:00:00 EDT 2020

A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters.

Toxicology and applied pharmacology

Wang Y,Zhu Y,Niu J,Deng Q,Guo S,Jiang H,Peng Z,Xue Y,Peng H,Xuan L,Pan G

Thu Oct 01 00:00:00 EDT 2020

Hepatic HuR modulates lipid homeostasis in response to high-fat diet.

Nature communications

Zhang Z,Zong C,Jiang M,Hu H,Cheng X,Ni J,Yi X,Jiang B,Tian F,Chang MW,Su W,Zhu L,Li J,Xiang X,Miao C,Gorospe M,de Cabo R,Dou Y,Ju Z,Yang J,Jiang C,Yang Z,Wang W

Tue Jun 16 00:00:00 EDT 2020

Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.

Frontiers in immunology

Zong X,Cao X,Wang H,Xiao X,Wang Y,Lu Z

Mon Sep 28 00:00:00 EDT 2020

Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.

EMBO reports

Zhang Y,Li C,Hu C,Wu Q,Cai Y,Xing S,Lu H,Wang L,Huang D,Sun L,Li T,He X,Zhong X,Wang J,Gao P,Smith ZJ,Jia W,Zhang H

Fri Oct 04 00:00:00 EDT 2019

The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.

Cell death & disease

Liu G,Wang K,Kuang S,Cao R,Bao L,Liu R,Liu H,Sun C

Thu Jun 07 00:00:00 EDT 2018

The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death.

Cell death & disease

Liu G,Wang K,Kuang S,Cao R,Bao L,Liu R,Liu H,Sun C

Thu Jun 07 00:00:00 EDT 2018

GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.

PloS one

Wang C,Li L,Liu S,Liao G,Li L,Chen Y,Cheng J,Lu Y,Liu J

Mon Jun 25 00:00:00 EDT 2018

GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.

PloS one

Wang C,Li L,Liu S,Liao G,Li L,Chen Y,Cheng J,Lu Y,Liu J

Mon Jun 25 00:00:00 EDT 2018

A novel transgenic mouse model of lysosomal storage disorder.

American journal of physiology. Gastrointestinal and liver physiology

Ortiz-Miranda S,Ji R,Jurczyk A,Aryee KE,Mo S,Fletcher T,Shaffer SA,Greiner DL,Bortell R,Gregg RG,Cheng A,Hennings LJ,Rittenhouse AR

Tue Nov 01 00:00:00 EDT 2016

Bioinformatics

Protein Aliases: 14 kDa selenium-binding protein; fatty acid binding protein 1, liver; fatty acid binding protein liver; Fatty acid-binding protein 1; Fatty acid-binding protein, liver; L-FABP; Liver-type fatty acid-binding protein; p14; SCP; Squalene- and sterol-carrier protein; Z-protein

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Gene Aliases: FABP1; FABPL; Fabplg; L-FABP; p14; SCP; SCP.

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UniProt ID: (Human) P07148, (Mouse) P12710, (Rat) P02692

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Entrez Gene ID: (Human) 2168, (Mouse) 14080, (Rat) 24360

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Function(s)

chromatin binding long-chain fatty acid transporter activity fatty acid binding protein binding phospholipid binding drug binding antioxidant activity bile acid binding transporter activity lipid binding lysophospholipid transporter activity

Process(es)

positive regulation of defense response to virus by host positive regulation of cell proliferation long-chain fatty acid transport triglyceride catabolic process positive regulation of fatty acid beta-oxidation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process cellular lipid metabolic process intestinal absorption positive regulation of hydrolase activity cellular response to hydrogen peroxide cellular response to hypoxia mitophagy in response to mitochondrial depolarization xenophagy cellular oxidant detoxification transport mitotic nuclear division lysophospholipid transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FABP1 Polyclonal Antibody

FABP1 Antibody (13626-1-AP) in WB

Product Details

13626-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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