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Invitrogen
FAM132A Polyclonal Antibody
Product Details
PA5-46452
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human FAM132A
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2607465
Product Specific Information
Peptide sequence: MRRWAWAAVV VLLGPQLVLL GGVGARREAQ RTQQPGQRAD PPNATASASS
Sequence homology: Human: 100%; Zebrafish: 82%
Target Information
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adipolin; Adipose-derived insulin-sensitizing factor; C1q and TNF related protein 12; C1q domain containing 2; C1q/TNF-related protein 12; Complement C1q tumor necrosis factor-related protein 12; family with sequence similarity 132, member A; protein FAM132A
Gene Aliases: C1QDC2; C1QTNF12; CTRP12; FAM132A
UniProt ID: (Human) Q5T7M4
Entrez Gene ID: (Human) 388581
positive regulation of insulin secretion involved in cellular response to glucose stimulus
negative regulation of gluconeogenesis
regulation of glucose import
positive regulation of glucose import
positive regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
positive regulation of protein kinase B signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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