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Product Details
PA5-80277
Product Specifications
Species Reactivity
Dog
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Canine aFGF/FGF1 protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787608
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Canine aFGF/FGF1.
Target Information
FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acidic fibroblast growth factor; Endothelial cell growth factor; FGF; Fibroblast growth factor; H-FGF-a; Heparin-binding growth factor 1; M-FGF-a
Gene Aliases: aFGF; ECGF; FGF-1; HBGF-1
Entrez Gene ID: (Dog) 607724
activation of MAPK activity
angiogenesis
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of endothelial cell migration
cell differentiation
positive regulation of cell migration
activation of protein kinase B activity
cellular response to heat
positive regulation of cholesterol biosynthetic process
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
positive regulation of cell division
branch elongation involved in ureteric bud branching
mesonephric epithelium development
regulation of endothelial tube morphogenesis
positive regulation of intracellular signal transduction
positive regulation of sprouting angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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