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Invitrogen
FGF16 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 5
FGF16 Antibody (PA5-47988) in ICC/IF
Immunocytochemistry analysis of FGF16 in immersion fixed human induced pluripotent stem (iPS) cells differentiated into cardiomyocytes. Samples were incubated in FGF16 polyclonal antibody (Product # PA5-47988) using a dilution of 8 µg/mL for 3 hours at room temperature followed by NorthernLights™ 493-conjugated Anti-Sheep IgG Secondary Antibody (green) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm.
Product Details
PA5-47988
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human FGF-16 Ala2-Arg207
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610278
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) FGF acidic, rhFGF basic, rhFGF-3, -4, -5, -6, -7, -9, -10, -11, -12, -13, -17, -18, -19, -21, -23, recombinant mouse (rm) FGF-8b, and rmFGF-15 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
FGF-16 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-16 signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-16; Fibroblast growth factor; Fibroblast growth factor 16; metacarpal 4-5 fusion
Gene Aliases: FGF-16; FGF16; MF4
UniProt ID: (Human) O43320, (Mouse) Q9ESL8
Entrez Gene ID: (Human) 8823, (Mouse) 80903
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
fibroblast growth factor receptor binding
growth factor activity
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
receptor binding
growth factor
intercellular signal molecule
MAPK cascade
regulation of endothelial cell proliferation
signal transduction
cell-cell signaling
metabolic process
fibroblast growth factor receptor signaling pathway
response to temperature stimulus
organ morphogenesis
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
regulation of MAP kinase activity
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of brown fat cell proliferation
regulation of sprouting angiogenesis
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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