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Invitrogen
FGF21 Recombinant Rabbit Monoclonal Antibody (JA10-97)
Product Details
MA5-32652
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JA10-97
Immunogen
Synthetic peptide within Human FGF21 aa 30-79
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2809929
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FGF; FGF-21; FGFL; Fibroblast growth factor; Fibroblast growth factor 21; PRO10196
Gene Aliases: FGF21; UNQ3115/PRO10196
UniProt ID: (Human) Q9NSA1, (Mouse) Q9JJN1
Entrez Gene ID: (Human) 26291, (Rat) 170580, (Mouse) 56636
signal transduction
cell-cell signaling
positive regulation of cell proliferation
regulation of low-density lipoprotein particle clearance
response to activity
endoplasmic reticulum unfolded protein response
response to nutrient levels
cellular response to drug
positive regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of glucose import
positive regulation of ERK1 and ERK2 cascade
cellular response to glucose stimulus
cellular response to low-density lipoprotein particle stimulus
endothelial cell apoptotic process
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
negative regulation of endothelial cell apoptotic process
fibroblast growth factor receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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