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FZD1 Antibody (PA5-115257) in IHC (P)
Immunohistochemistry analysis of FZD1 in rat liver tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115257) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115257
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FZD1(Accession Q9UP38), corresponding to amino acid residues L21-R71.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899893
Product Specific Information
Antibody detects endogenous levels of total FZD1.
Target Information
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chfz-1; Dfrizzled-1; DKFZp564G072; Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 1; FLJ95923; frizzled; frizzled 1; frizzled 1, seven transmembrane spanning receptor; frizzled family receptor 1; frizzled homolog 1; frizzled, Drosophila, homolog of, 1; Frizzled-1; Fz receptor 1; Fz-1; FzE1; hFz1; rFz1; Wnt receptor; Xfrizzled-1
Gene Aliases: FZD1
UniProt ID: (Human) Q9UP38
Entrez Gene ID: (Human) 8321, (Rat) 58868
positive regulation of protein phosphorylation
membranous septum morphogenesis
muscular septum morphogenesis
outflow tract morphogenesis
G-protein coupled receptor signaling pathway
cell-cell signaling
synapse assembly
neuron differentiation
negative regulation of BMP signaling pathway
epithelial cell differentiation
negative regulation of catenin import into nucleus
autocrine signaling
non-canonical Wnt signaling pathway
response to drug
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
lung alveolus development
positive regulation of sequence-specific DNA binding transcription factor activity
hard palate development
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
cellular response to vitamin D
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
negative regulation of canonical Wnt signaling pathway
planar cell polarity pathway involved in neural tube closure
beta-catenin destruction complex disassembly
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
Wnt signaling pathway
ventricular septum morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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