Invitrogen

FZD1 Polyclonal Antibody

View all (10) FZD1 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-88045

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 548-647 of human FZD1 (NP_0034961)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804613

Product Specific Information

Positive Samples: Mouse eye, Mouse kidney, Mouse lung, Rat brain; Cellular Location: Cell membrane, Membrane, Multi-pass membrane protein

Immunogen sequence: TRLTNSKQGE TTV

Target Information

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Chfz-1; Dfrizzled-1; DKFZp564G072; FLJ95923; frizzled; frizzled 1; frizzled 1, seven transmembrane spanning receptor; frizzled family receptor 1; frizzled homolog 1; frizzled, Drosophila, homolog of, 1; Frizzled-1; Fz receptor 1; Fz-1; FzE1; hFz1; mFz1; Wnt receptor; Xfrizzled-1

View more View less

Gene Aliases: AW227548; FZ-1; Fz1; FZD1

View more View less

UniProt ID: (Human) Q9UP38, (Mouse) O70421

View more View less

Entrez Gene ID: (Human) 8321, (Mouse) 14362

View more View less

Function(s)
G-protein coupled receptor activity receptor binding frizzled binding protein binding Wnt-protein binding PDZ domain binding Wnt-activated receptor activity signal transducer activity transmembrane signaling receptor activity identical protein binding protein homodimerization activity protein heterodimerization activity transmembrane signal receptor
Process(es)
positive regulation of protein phosphorylation membranous septum morphogenesis muscular septum morphogenesis outflow tract morphogenesis G-protein coupled receptor signaling pathway cell-cell signaling synapse assembly neuron differentiation negative regulation of BMP signaling pathway epithelial cell differentiation negative regulation of catenin import into nucleus autocrine signaling non-canonical Wnt signaling pathway response to drug canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation canonical Wnt signaling pathway involved in osteoblast differentiation regulation of osteoblast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated lung alveolus development positive regulation of sequence-specific DNA binding transcription factor activity hard palate development canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway cellular response to vitamin D cellular response to growth factor stimulus cellular response to peptide hormone stimulus negative regulation of canonical Wnt signaling pathway planar cell polarity pathway involved in neural tube closure beta-catenin destruction complex disassembly Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation signal transduction cell surface receptor signaling pathway multicellular organism development Wnt signaling pathway ventricular septum morphogenesis
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support