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Product Details
29993-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VPRELSGSSP VLEETHPAHQ QGASRPGPRD AQAHPGRPRA VPTQCDVPPN SRFDCAPDKA ITQEQCEARG CCYIPAKQGL QGAQMGQPWC FFPPSYPSYK LENLSSSEMG YTATLTRTTP TFFPKDILTL RLDVMMETEN RLHFTIKDPA NRRYEVPLET PHVHSRAPSP LYSVEFSEEP FGVIVRRQLD GRV
Target Information
This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acid maltase; Aglucosidase alfa; Lysosomal alpha-glucosidase
Gene Aliases: E430018M07Rik; GAA; LYAG
UniProt ID: (Human) P10253, (Mouse) P70699
Entrez Gene ID: (Human) 2548, (Mouse) 14387
maltose metabolic process
regulation of the force of heart contraction
diaphragm contraction
heart morphogenesis
glycogen catabolic process
sucrose metabolic process
glucose metabolic process
lysosome organization
locomotory behavior
tissue development
vacuolar sequestering
muscle cell cellular homeostasis
neuromuscular process controlling posture
neuromuscular process controlling balance
cardiac muscle contraction
carbohydrate metabolic process
glycogen metabolic process
striated muscle contraction
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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