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FIGURE: 1 / 1
GABRA2 Antibody (PA1-4713) in WB
Western blot of GABRA2 in mouse brain lysates from wild type and alpha 2-knockout animals showing specific immunolabeling of a band at ~51 kDa corresponding to the alpha 2-subunit of the GABRA2 polyclonal antibody (Product # PA1-4713). The labeling was absent from a lysate prepared from alpha 2-knockout animals.
Product Details
PA1-4713
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein from the cytoplasmic loop of the alpha 2 subunit of rat GABRA2
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2108833
Product Specific Information
PA1-4713 is specific for the ~51k alpha-2-subunit of the GABAA receptor. In Western blot, labeling is absent in alpha-2-subunit knockout animals.
This antibody is predicted to react with bovine, canine, human, non-human primate and Zebrafish based on 100% sequence homology.
Target Information
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ97076; GABA(A) receptor subunit alpha-2; GABAAR subunit alpha-2; GABAARalpha2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid receptor A2 subunit; Gamma-aminobutyric acid receptor subunit alpha-2
Gene Aliases: C630048P16Rik; Gabra-2; Gabra2
UniProt ID: (Mouse) P26048
Entrez Gene ID: (Mouse) 14395, (Rat) 289606
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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