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GABRA2 Antibody (PA5-119917) in WB
Western blot analysis of GABRA2 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. GABRA2 Polyclonal Antibody (Product # PA5-119917) at 1:1,000 was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:200,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: Mouse brain tissue lysate. Lane 2: Mouse cerebellum tissue lysate. Lane 3: Human brain tissue lysate.
Product Details
PA5-119917
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within human GABRA2 aa 29-200/451 (Extracellular)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2913489
Product Specific Information
Positive Control: Rat brain tissue lysates, mouse brain tissue lysate, mouse cerebellum tissue lysate, human brain tissue lysate.
Subcellular Location: Postsynaptic cell membrane, Cell membrane, Cytoplasmic vesicle membrane, Dendrite.
Target Information
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ97076; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; GABAAR subunit alpha-2; GABAARalpha2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid A receptor alpha 2; gamma-aminobutyric acid receptor A2 subunit; Gamma-aminobutyric acid receptor subunit alpha-2
Gene Aliases: C630048P16Rik; Gabra-2; GABRA2
UniProt ID: (Human) P47869, (Mouse) P26048
Entrez Gene ID: (Human) 2555, (Mouse) 14395, (Rat) 289606
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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