Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: VNWYAPLVA PISKDRTICT VPLIDVINGN TYEIIPQGGG DEDGYARGAW DWSMLWKRVP LTPQEKRLRK TKTEPYRSPA MAGGLFAIER EFFFELGLYD PGLQIWGGEN FEISYKIWQC GGKLLFVPCS RVGHIYRLEG WQGNPPPIYV GSSPTLKNYV RVVEVWWDEY KDYFYASRPE SQALPYGDIS ELKKFREDHN CKSFKWFMEE IAYDITSHYP LPPKNVDWGE IRGFETAYCI DSMGKTNGGF VELGPCHRMG GNQLFRINEA NQLMQYDQCL TKGADGSKVM ITHCNLNEFK EWQYFKNLHR FTHIPSGKCL DRSEVLHQVF ISNCDSSKTT QKWEMNNIHS V (308-657 aa encoded by BC047468)
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GalNAc-T7; N-acetylgalactosaminyltransferase 7; Polypeptide GalNAc transferase 7; pp-GaNTase 7; ppGaNTase-T7; Protein-UDP acetylgalactosaminyltransferase 7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
Gene Aliases: AI225872; GALNAC-T7; GalNAcT7; GALNT7
UniProt ID: (Human) Q86SF2, (Mouse) Q80VA0, (Rat) Q9R0C5
Entrez Gene ID: (Human) 51809, (Mouse) 108150, (Rat) 29750
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