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Product Details
PA5-89484
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human GANAB (NP_0012651231)
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805600
Product Specific Information
Immunogen sequence: MTRFRIDELE PRRPRYRVPD VLVADPPIAR LSVSGRDENS VELTMAEGPY KIILTARPFR LDLLEDRSLL LSVNARGLLE FEHQRAPRVS QGSKDPAEGD GAQPEETPRD GDKPEETQGK AEKDEPGAWE ETFKTHSDSK PYGPMSVGLD FSLPGMEHVY GIPEHADNLR LKVTEGGEPY RLYNLDVFQY ELYNPMALYG SVPVLLAHNP HRDLGIFWLN AAETWVDISS NTAGKTLFGK MMDYLQGSGE TPQTDVRWMS; Positive Samples: U-87MG, Raji, HepG2, HeLa, Mouse brain, Mouse liver, Rat brain; Cellular Location: Endoplasmic reticulum, Golgi apparatus, Melanosome
Target Information
This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha glucosidase 2 alpha neutral subunit; Alpha-glucosidase 2; carbohydrate processing enzyme of the endoplasmic reticulum; glucosidase II alpha-subunit; Glucosidase II subunit alpha; neutral AB; Neutral alpha-glucosidase AB
Gene Aliases: AU042638; G2AN; GANAB; GIIA; GLUII; KIAA0088; mKIAA0088
UniProt ID: (Human) Q14697, (Mouse) Q8BHN3
Entrez Gene ID: (Human) 23193, (Mouse) 14376, (Rat) 293721
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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