Invitrogen

GAS6 Polyclonal Antibody

View all (11) GAS6 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-121208

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human GAS6 (NP_000811.1).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.25 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914780

Product Specific Information

Positive test controls include: HeLa, NCI-H460, HT-1080, SW620, DU145. The target is usually found in the following locations: Secreted.

Immunogen sequence: GSPYTKNSGF ATCVQNLPDQ CTPNPCDRKG TQACQDLMGN FFCLCKAGWG GRLCDKDVNE CSQENGGCLQ ICHNKPGSFH CSCHSGFELS SDGRTCQDID ECADSEACGE ARCKNLPGSY SCLCDEGFAY SSQEKACRDV DECLQGRCEQ VCVNSPGSYT CHCDGRGGLK LSQDMDTCED ILPCVPFSVA KSVKSLYLGR M

Target Information

This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: AXL receptor tyrosine kinase ligand; AXL stimulatory factor; GAS 6; GAS-6; growth arrest-specific 6; Growth arrest-specific protein 6

View more View less

Gene Aliases: AXLLG; AXSF; Gas-6; GAS6

View more View less

UniProt ID: (Human) Q14393, (Mouse) Q61592

View more View less

Entrez Gene ID: (Human) 2621, (Mouse) 14456

View more View less

Function(s)
phosphatidylserine binding receptor binding voltage-gated calcium channel activity calcium ion binding protein binding protein tyrosine kinase activator activity receptor tyrosine kinase binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process receptor agonist activity binding, bridging metal ion binding extracellular matrix protein
Process(es)
neuron migration positive regulation of protein phosphorylation positive regulation of cytokine-mediated signaling pathway platelet degranulation positive regulation of glomerular filtration signal peptide processing protein phosphorylation ER to Golgi vesicle-mediated transport phagocytosis apoptotic process cell cycle arrest cell adhesion signal transduction enzyme linked receptor protein signaling pathway cell proliferation cellular response to starvation positive regulation of gene expression negative regulation of tumor necrosis factor-mediated signaling pathway macrophage cytokine production cell migration peptidyl-serine phosphorylation fusion of virus membrane with host plasma membrane viral genome replication platelet activation organ regeneration cell-substrate adhesion positive regulation of TOR signaling activation of protein kinase B activity negative regulation of interferon-gamma production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of natural killer cell differentiation positive regulation of peptidyl-serine phosphorylation negative regulation of protein import into nucleus, translocation cellular response to interferon-alpha cellular response to drug B cell chemotaxis regulation of growth negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic cell clearance negative regulation of sequence-specific DNA binding transcription factor activity protein kinase B signaling positive regulation of protein kinase activity negative regulation of transcription, DNA-templated viral entry into host cell receptor-mediated virion attachment to host cell positive regulation of protein export from nucleus positive regulation of fibroblast proliferation negative regulation of interleukin-1 secretion positive regulation of phagocytosis leukocyte migration positive regulation of protein kinase B signaling positive regulation of protein tyrosine kinase activity negative regulation of biomineral tissue development positive regulation of ERK1 and ERK2 cascade platelet aggregation calcium ion transmembrane transport cellular response to vitamin K cellular response to glucose stimulus cellular response to growth factor stimulus protein targeting to plasma membrane extracellular matrix assembly dendritic cell differentiation hematopoietic stem cell migration to bone marrow negative regulation of oligodendrocyte apoptotic process negative regulation of interleukin-6 secretion negative regulation of fibroblast apoptotic process negative regulation of endothelial cell apoptotic process positive regulation of dendritic cell chemotaxis negative regulation of renal albumin absorption negative regulation of dendritic cell apoptotic process blood coagulation regulation of ion transmembrane transport positive regulation of receptor activity
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support