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Product Details
PA5-115285
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human GGPS1(Accession O95749), corresponding to amino acid residues E171-I221.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899921
Product Specific Information
Antibody detects endogenous levels of total GGPS1.
Target Information
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; geranylgeranyl pyrophosphate synthetase; Geranyltranstransferase; GGPP synthase; GGPP synthetase; GGPPSase
Gene Aliases: 1810026C22Rik; 9530089B04Rik; AI843169; C79210; Crlf3; GGPPS; GGPPS1; GGPS1; rGGPS1a; rGGPS1a1; rGGPS1a2; rGGPS1a3
UniProt ID: (Human) O95749, (Rat) Q6F596, (Mouse) Q9WTN0
Entrez Gene ID: (Human) 9453, (Rat) 291211, (Mouse) 14593
dimethylallyltranstransferase activity
farnesyltranstransferase activity
geranyltranstransferase activity
protein binding
metal ion binding
prenyltransferase activity
protein geranylgeranyltransferase activity
protein prenyltransferase activity
4-hydroxybenzoate octaprenyltransferase activity
protoheme IX farnesyltransferase activity
transferase activity
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity
cadaverine aminopropyltransferase activity
agmatine aminopropyltransferase activity
1,4-dihydroxy-2-naphthoate octaprenyltransferase activity
trans-pentaprenyltranstransferase activity
ATP dimethylallyltransferase activity
ADP dimethylallyltransferase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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