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Product Details
PA5-121195
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human GHRHR (NP_000814.2).
Conjugate
Form
Liquid
Concentration
1.56 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914767
Product Specific Information
Positive test controls include: U-251MG, Mouse brain, Rat brain. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein.
Immunogen sequence: MDRRMWGAHV FCVLSPLPTV LGHMHPECDF ITQLREDESA CLQAAEEMPN TTLGCPATWD GLLCWPTAGS GEWVTLPCPD FFSHFSSESG AVKRDCTITG WSEPFPPYPV ACPVPLELLA EEESYFSTVK
Target Information
Growth Hormone Releasing Hormone (GHRH) is a member of a family of peptide hormones that also includes VIP (vasoactive intestinal polypeptide) and PACAP (pituitary adenylate cyclase-activating polypeptide). It is a hypothalamic peptide that binds to G-protein coupled receptors to stimulate secretion and synthesis of growth hormone (GH). GHRH receptor proteins have been identified on the plasma membrane of primary human tumor cells, and are thought to be involved in the growth of a variety of cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GHRH receptor; Ghrh-r; GHRHRpsv; GRF receptor; GRFR; Growth hormone - releasing receptor; Growth hormone-releasing factor receptor; Growth hormone-releasing hormone receptor
Gene Aliases: GHRFR; GHRHR; GHRHREC; GRFR; IGHD1B; lit; little
UniProt ID: (Human) Q02643, (Rat) Q02644, (Mouse) P32082
Entrez Gene ID: (Human) 2692, (Rat) 25321, (Mouse) 14602
cell surface receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
lactation
positive regulation of cell proliferation
determination of adult lifespan
cAMP-mediated signaling
water homeostasis
growth hormone secretion
positive regulation of cAMP biosynthetic process
response to insulin
cellular response to insulin stimulus
regulation of intracellular steroid hormone receptor signaling pathway
positive regulation of multicellular organism growth
hormone metabolic process
positive regulation of insulin-like growth factor receptor signaling pathway
response to estrogen
positive regulation of circadian sleep/wake cycle, non-REM sleep
cell maturation
multicellular organismal reproductive process
regulation of protein metabolic process
response to glucocorticoid
positive regulation of growth hormone secretion
somatotropin secreting cell development
cellular response to glucose stimulus
signal transduction
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenohypophysis development
positive regulation of cAMP metabolic process
mammary gland development
regulation of growth
regulation of insulin-like growth factor receptor signaling pathway
positive regulation of hormone secretion
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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