Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: DLDDQHDYDS VASDEDTDQE PLRSTGATRS NRARSMDSSD LSDGAVTLQE YLELKKALAT SEAKVQQLMK VSSSLSDELR RLQREIHKLQ AENLQLRQPP GPVPTPPLPS ERAEHTPMAP GGSTHRRDRQ AFSMYEPGSA L
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARF GAP GIT1; ARF GTPase-activating protein GIT1; CAT-1; CAT1; Cool-associated and tyrosine-phosphorylated protein 1; G protein-coupled receptor kinase interacting ArfGAP 1; G protein-coupled receptor kinase interactor 1; G protein-coupled receptor kinase-interactor 1; GRK-interacting protein 1; p95-APP1
Gene Aliases: GIT1
UniProt ID: (Human) Q9Y2X7
Entrez Gene ID: (Human) 28964
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