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Product Details
PA5-57159
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GKAP1. Recombinant protein control fragment (Product #RP-95675).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642016
Product Specific Information
Immunogen sequence: ITQWEAKYKE VKARNAQLLK MLQEGEMKDK AEILLQVDES QSIKNELTIQ VTSLHAALEQ ERSKVKVLQA ELAKYQGGRK GKRNSESDQC R
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Target Information
The approximately 142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 42 kD cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein 42kDa; cGMP-dependent protein kinase-anchoring protein of 42 kDa; G kinase-anchoring protein 1; protein kinase anchoring protein GKAP42
Gene Aliases: 42kDa; 4933400B15Rik; D13Ertd340e; FKSG21; GKAP1; GKAP42
UniProt ID: (Human) Q5VSY0, (Mouse) Q9JMB0
Entrez Gene ID: (Human) 80318, (Mouse) 56278
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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