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Product Details
PA5-95966
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 329-677 of human GLB1 (NP_0003953)
Conjugate
Form
Liquid
Concentration
2.64 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807768
Product Specific Information
Immunogen sequence: TSYDYDAPLS EAGDLTEKYF ALRNIIQKFE KVPEGPIPPS TPKFAYGKVT LEKLKTVGAA LDILCPSGPI KSLYPLTFIQ VKQHYGFVLY RTTLPQDCSN PAPLSSPLNG VHDRAYVAVD GIPQGVLERN NVITLNITGK AGATLDLLVE NMGRVNYGAY INDFKGLVSN LTLSSNILTD WTIFPLDTED AVCSHLGGWG HRDSGHHDEA WAHNSSNYTL PAFYMGNFSI PSGIPDLPQD TFIQFPGWTK GQVWINGFNL GRYWPARGPQ LTLFVPQHIL MTSAPNTITV LELEWAPCSS DDPELCAVTF VDRPVIGSSV TYDHPSKPVE KRLMPPPPQK NKDSWLDHV
Positive Samples: A549, HeLa, Mouse kidney; Cellular Location: Cytoplasm, Lysosome, perinuclear region
Target Information
Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene have been associated with GM1-gangliosidosis and Morquio B syndrome. Diseases associated with GLB1 include Gm1-Gangliosidosis, Type I and Gm1-Gangliosidosis, Type Ii.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acid beta-galactosidase; Beta-Gal; Beta-galactosidase; betagal; bgal; Elastin receptor 1; elastin receptor 1, 67kDa; Lactase; ß-gal; ß-galactosidase; ßgal
Gene Aliases: AW125515; Bge; Bgl; Bgl-e; Bgl-s; Bgl-t; Bgs; Bgt; C130097A14Rik; EBP; ELNR1; Glb-1; GLB1; MPS4B
UniProt ID: (Human) P16278, (Mouse) P23780
Entrez Gene ID: (Human) 2720, (Rat) 316033, (Mouse) 12091
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