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The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutathione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
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Protein Aliases: Aldoketomutase; epididymis secretory protein Li 74; Glx I; glyoxalase 1 complex; glyoxalase 1 regulatory; glyoxalase 1 structural; glyoxalase domain containing 1; Glyoxalase I; glyoxylase 1; Ketone-aldehyde mutase; lactoyl glutathione lyase; Lactoylglutathione lyase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase
Gene Aliases: 0610009E22Rik; 1110008E19Rik; 2510049H23Rik; AW550643; Glo-1; Glo-1r; Glo-1s; GLO1; Glo1-r; Glo1-s; GLOD1; GLY1; GLYI; HEL-S-74; Qglo
UniProt ID: (Human) Q04760, (Rat) Q6P7Q4, (Mouse) Q9CPU0
Entrez Gene ID: (Human) 2739, (Rat) 294320, (Mouse) 109801
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