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Product Details
55167-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to GNAT1.
Target Information
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; Guanine nucleotide-binding protein G(t) subunit alpha-1; guanine nucleotide-binding protein G(T), alpha-1 subunit; rod-type transducin alpha subunit; Tr alpha; Transducin alpha-1 chain; transducin, rod-specific
Gene Aliases: CSNB1G; CSNBAD3; GBT1; Gnat-1; GNAT1; GNATR; Ird1; Ird2; irdc; irdr; Tralpha; transducin
UniProt ID: (Human) P11488, (Mouse) P20612
Entrez Gene ID: (Human) 2779, (Mouse) 14685
detection of chemical stimulus involved in sensory perception of bitter taste
protein folding
signal transduction
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
visual perception
phototransduction, visible light
cell proliferation
response to light stimulus
response to light intensity
rhodopsin mediated signaling pathway
regulation of rhodopsin mediated signaling pathway
eye photoreceptor cell development
detection of light stimulus involved in visual perception
sensory perception of umami taste
positive regulation of cyclic-nucleotide phosphodiesterase activity
negative regulation of cyclic-nucleotide phosphodiesterase activity
retina development in camera-type eye
cellular response to electrical stimulus
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
phototransduction
response to stimulus
Performance Guarantee
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