Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Alomone Labs, LTD
Ghrelin Receptor (GHSR) (extracellular) Polyclonal Antibody, FITC
FIGURE: 1 / 2
Ghrelin Receptor (GHSR) (extracellular) Antibody (AGR-031-F-50UL) in Flow
Cell surface detection of Ghrelin receptor in live intact human THP-1 monocytic leukemia cells: - (black line) cells. (red) Cells + rabbit IgG isotype control-FITC. (green) Cells + Anti-Ghrelin Receptor (GHSR) (extracellular)-FITC Antibody (#AGR-031-F), (5 µg).
Product Details
AGR-031-F-50UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CRATEFAVRSG, corresponding to amino acid residues 197-207 of rat Ghrelin receptor, 2nd extracellular loop
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Lyophilized
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Growth hormone secretagogue receptor 1a (GHSR) is a member of the G-protein coupled receptor family. GHSR may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations to the gene can cause isolated partial growth hormone deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: G-protein coupled receptor; GH-releasing peptide receptor; Ghrelin receptor; GHRP; Ghrp receptor; GHS receptor; GHS-R; Growth hormone secretagogue receptor type 1
Gene Aliases: C530020I22Rik; GHDP; GHSR
UniProt ID: (Human) Q92847, (Mouse) Q99P50, (Rat) O08725
Entrez Gene ID: (Human) 2693, (Mouse) 208188, (Rat) 84022
G-protein coupled receptor signaling pathway
actin polymerization or depolymerization
adult feeding behavior
response to hormone
hormone-mediated signaling pathway
growth hormone secretion
response to food
positive regulation of appetite
negative regulation of interleukin-1 beta production
cellular response to insulin stimulus
positive regulation of multicellular organism growth
negative regulation of tumor necrosis factor biosynthetic process
regulation of hindgut contraction
positive regulation of insulin-like growth factor receptor signaling pathway
negative regulation of interleukin-6 biosynthetic process
positive regulation of fatty acid metabolic process
negative regulation of insulin secretion
decidualization
negative regulation of inflammatory response
regulation of synapse assembly
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support