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Glucose-6-phosphatase (G6PC) is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G-6-Pase 2; G6Pase 2; Glucose-6-phosphatase 2; glucose-6-phosphatase, catalytic, 2; glucose-6-phosphatase, catalytic, related sequence; islet-specific G6CP-related protein; Islet-specific glucose-6-phosphatase catalytic subunit-related protein; islet-specific glucose-6-phosphatase-related protein; similar to glucose-6-phosphatase, catalytic, related
Gene Aliases: G6pc-rs; G6PC2; IGRP
UniProt ID: (Human) Q9NQR9, (Mouse) Q9Z186
Entrez Gene ID: (Human) 57818, (Mouse) 14378, (Rat) 681817
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