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RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594). Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre-mRNA splicing regulation (PubMed:19523114). Binds (via C-terminus) to poly(U) RNA (PubMed:19523114). Involved in mRNA translation regulation, probably at the initiation step (PubMed:21771594). Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromodomain helicase DNA binding protein 3 interacting protein; HABP4; Hyaluronan-binding protein 4; hyaluronic acid binding protein 4; Hyaluronic acid-binding protein 4; hyaluronic acid-binding protein 4 (intracellular); IHABP-4; IHABP4; intracellular antigen detected by monoclonal antibody Ki-1; Intracellular hyaluronan-binding protein 4; intracellular hyaluronan-binding protein p57; Ki-1/57 intracellular antigen
Gene Aliases: 4933413D03Rik; 4933428J01Rik; HABP4; IHABP-4; IHABP4; Ki-1/57; SERBP1L
UniProt ID: (Human) Q5JVS0, (Rat) A1L1K8, (Mouse) Q9JKS5
Entrez Gene ID: (Human) 22927, (Rat) 361196, (Mouse) 56541
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