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Histone acetyltransferase localized in the Golgi apparatus that mediates acetylation of free histone H4, thereby facilitating nucleosome assembly. Has a preference for free histone H4 'Lys-20'(H4K20ac), 'Lys-79'(H4K79ac) and 'Lys-91' (H4K91ac). Also displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase.
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Protein Aliases: GNAT acetyltransferase; GNAT acetytransferase; HAT4; Histone acetyltransferase type B protein 4; hNaa60; N-acetyltransferase 15; N-acetyltransferase 15 (GCN5-related, putative); N-alpha-acetyltransferase 60; N-alpha-acetyltransferase F; NatF; natF catalytic subunit
Gene Aliases: 1200013P24Rik; AI315146; HAT4; NAA60; NAT15; RGD1308915; UNQ2771/PRO7155
UniProt ID: (Human) B4DYC4, (Mouse) Q9DBU2, (Rat) Q3MHC1
Entrez Gene ID: (Human) 79903, (Mouse) 74763, (Rat) 363545
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