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HBB Antibody (PA5-85432) in WB
Western Blot using HBB Polyclonal Antibody (Product # PA5-85432). Untreated (–) and treated (+) mouse tissue extracts (30 µg) were separated by 15% SDS-PAGE, and the membrane was blotted with HBB Polyclonal Antibody (Product # PA5-85432) diluted at 1:500. (CFA: Complete Freunds adjuvant).
Product Details
PA5-85432
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human Hemoglobin beta Recombinant protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792572
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Rat (81%), Pig (85%), Sheep (81%), Rhesus Monkey (94%), Bovine (84%).
Positive Control: human plasma, Mouse Leukocyte, mouse leukocyte treated with CFA, rat spleen.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon-gamma-G-gamma-A-delta-beta-3'.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta globin chain; Beta-1-globin; Beta-globin; hemoglobin beta; Hemoglobin beta chain; hemoglobin beta chain complex; Hemoglobin beta chain, major-form; Hemoglobin beta-1 chain; Hemoglobin subunit beta; Hemoglobin subunit beta-1; hemoglobin, beta; III beta-1 globin; III beta-2 globin
Gene Aliases: beta-globin; CD113t-C; HBB
UniProt ID: (Human) P68871, (Rat) P02091
Entrez Gene ID: (Human) 3043, (Rat) 24440
glutathione metabolic process
regulation of eIF2 alpha phosphorylation by heme
oxygen transport
hemopoiesis
erythrocyte development
protein heterooligomerization
receptor-mediated endocytosis
blood coagulation
regulation of blood pressure
positive regulation of cell death
bicarbonate transport
nitric oxide transport
response to hydrogen peroxide
hydrogen peroxide catabolic process
positive regulation of nitric oxide biosynthetic process
regulation of blood vessel size
renal absorption
platelet aggregation
cellular oxidant detoxification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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