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Product Details
H00204851-M05
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
4D5
Immunogen
HIPK1 (AAH28408, 330 a.a. approximately 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: CTPLMVATLH PQVATITPQY AVPFTLSCAA GRPALVEQTA AVLQAWPGGT QQILLPSTWQ QLPGVALHNS VQPTAMIPEA MGSGQQLADW RNAHSHGNQY S
Target Information
HIPK1 phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. The protein encoded by HIPK1 belongs to the Ser/Thr family of protein kinases and HIPK subfamily. Alternative splicing results in four transcript variants encoding four distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeodomain interacting protein kinase 1-like protein; Homeodomain-interacting protein kinase 1; nuclear body associated kinase 2b; Nuclear body-associated kinase 2
Gene Aliases: HIPK1; KIAA0630; MYAK; NBAK2
UniProt ID: (Human) Q86Z02
Entrez Gene ID: (Human) 204851
eye development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
smoothened signaling pathway
positive regulation of cell proliferation
anterior/posterior pattern specification
regulation of tumor necrosis factor-mediated signaling pathway
retina layer formation
neuron differentiation
adherens junction assembly
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of angiogenesis
embryonic camera-type eye morphogenesis
embryonic retina morphogenesis in camera-type eye
definitive hemopoiesis
lens induction in camera-type eye
iris morphogenesis
endothelial cell apoptotic process
extrinsic apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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