Proteintech

HMG20B Polyclonal Antibody

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View all (20) BRAF35 antibodies
Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Product Details

14582-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
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Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:500
-

Immunoprecipitation (IP)

0.5-4.0 µg
-

ChIP assay (ChIP)

Assay-dependent
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HMG20B Fusion Protein Ag6103 (73-284 aa encoded by BC002552)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: PVTGYVRFL NERREQIRTR HPDLPFPEIT KMLGAEWSKL QPTEKQRYLD EAEREKQQYM KELRAYQQSE AYKMCTEKIQ EKKIKKEDSS SGLMNTLLNG HKGGDCDGFS TFDVPIFTEE FLDQNKAREA ELRRLRKMNV AFEEQNAVLQ RHTQSMSSAR ERLEQELALE ERRTLALQQQ LQAVRQALTA SFASLPVPGT GETPTLGTLD FYM (73-284 aa encoded by BC002552)

Target Information

Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); BRCA2-associated factor 35; FLJ26127; high mobility group 20 B; high mobility group protein 20 B; high-mobility group 20B; HMG box domain containing 2; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; murine sarcoma viral (v-raf) oncogene homolog B1; p94; Proto-oncogene B-Raf; Serine/threonine-protein kinase B-raf; SMARCE1-related protein; Sox-like transcriptional factor; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1-related; v-raf murine sarcoma viral oncogene homolog B; v-Raf murine sarcoma viral oncogene homolog B1

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Gene Aliases: 9930012E13Rik; AA120551; AA387315; AA473386; AW610687; B-raf; B-RAF1; BRAF; Braf-2; BRAF1; Braf2; BRAF25; BRAF35; C230098H17; C87398; D6Ertd631e; HMG20B; HMGX2; HMGXB2; NS7; PP7706; pp8857; RAFB1; SMARCE1R; SOXL

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UniProt ID: (Human) P15056, (Mouse) P28028, (Human) Q9Y491, (Mouse) Q9Z104

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Entrez Gene ID: (Human) 673, (Rat) 114486, (Mouse) 109880, (Human) 10362, (Rat) 362825, (Mouse) 15353

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Function(s)
protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding small GTPase binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity nucleotide binding receptor signaling protein activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups metal ion binding DNA binding histone deacetylase activity chromatin binding four-way junction DNA binding transcription factor activity, sequence-specific DNA binding non-receptor serine/threonine protein kinase
Process(es)
MAPK cascade activation of MAPKK activity myeloid progenitor cell differentiation protein phosphorylation visual learning organ morphogenesis positive regulation of gene expression negative regulation of fibroblast migration glucose transport thyroid gland development positive regulation of peptidyl-serine phosphorylation somatic stem cell population maintenance cellular response to drug regulation of cell proliferation negative regulation of apoptotic process CD4-positive, alpha-beta T cell differentiation positive T cell selection response to peptide hormone negative regulation of neuron apoptotic process thymus development positive regulation of axon regeneration positive regulation of axonogenesis protein heterooligomerization positive regulation of stress fiber assembly response to cAMP long-term synaptic potentiation head morphogenesis face development positive regulation of ERK1 and ERK2 cascade cellular response to calcium ion establishment of protein localization to membrane positive regulation of substrate adhesion-dependent cell spreading negative regulation of synaptic vesicle exocytosis negative regulation of endothelial cell apoptotic process cell differentiation alpha-beta T cell differentiation regulation of axon regeneration signal transduction phosphorylation intracellular signal transduction transcription, DNA-templated regulation of transcription, DNA-templated cell cycle blood coagulation histone deacetylation negative regulation of protein sumoylation skeletal muscle cell differentiation positive regulation of neuron differentiation chromatin remodeling chromatin organization chromatin modification
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